What Causes Elevated Liver Elevated Alkaline Phosphatase Differential Diagnosis

Testing for alp primarily consists of obtaining a blood sample from a patient along with several other tests for the disorder in question that may be associated with the increase in alp in the blood serum.

National elevator industry pension plan icd 10 code for elevated triglycerides. If the ggt level was normal i would search for abnormalities of bone as the cause of the elevated alkaline phosphatase. Learning points if alkaline phosphatase is raised in an asymptomatic patient and serum bilirubin liver transaminases creatinine adjusted calcium thyroid function and blood count are normal. A 51 year old asymptomatic woman.

Also it appears in the biliary tract and the bone tissue. Indeed these blood tests may reflect problems arising outside the liver such as hemolysis elevated bilirubin level or bone disease elevated alkaline phosphatase ap level. In a significant proportion of these patients elevated ap is benign requiring no intervention.

Key tests for evaluating possible liver disease would include an ultrasound of the liver and biliary system and an anti mitochondrial antibody to look for primary biliary cirrhosis. Likewise concerning the diagnosis of non bone non liver causes of elevated alkaline phosphatase the diagnostic work up has the potential to be vast and should be guided by the clinical context. This article discusses the most common causes of raised alkaline phosphatase levels in an asymptomatic patient and provides advice on the relevant investigations.

See liver biochemical tests that detect injury to hepatocytes and enzymatic measures of cholestasis eg alkaline phosphatase 5 nucleotidase gamma glutamyl transpeptidase and classification and causes of jaundice or asymptomatic hyperbilirubinemia and tests of the livers biosynthetic capacity eg albumin coagulation factors. Learn about the possible causes of elevated liver enzymes and their symptoms and treatment options here. So it is found distribute in various forms known as isoenzymes originally from the liver and bones.

Elevated alkaline phosphatase is most commonly caused by liver disease or bone disorders. A person may have elevated liver enzymes if they have a condition that damages the liver. Due to the possibility of underlying hepatobiliaryor bone diseases the diagnostic work up of a child with elevated alkaline phosphatase ap levels can be quite costly.